Check out review by Amandine Guerin and Boris Striepen on the biology of Cryptosporidium. See why we find the cell biology of this unique parasite fascinating and learn about the many open questions. See paper in Cell Host & Microbe.
Our new paper describes a collaborative effort with the Broad Institute, the University of Vermont and others to develop novel treatments for cryptosporidiosis. In this study we provide the first rigorous genetic validation of a drug target in Cryptosporidium by using CRISPR/Cas9 directed engineering of drug resistance. Check it out at Science Translational Medicine